As a young medical student in Boston, Kate White is barely hanging on. The stress of interning at a top-tier teaching hospital, compounded by her father’s recent death and her upcoming wedding to a superstar surgeon are proving to be too much to handle. Meanwhile, somewhere deep in the depths of the hospital’s research laboratory, secretive experiments have stumbled upon a horrific breakthrough. As Kate finds each new test increasingly overwhelming, she becomes obsessed with seeking a way out, crossing all professional boundaries – and putting herself and her colleagues in harm’s way.